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3d models across experimental groups  (Oxford Instruments)


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    Oxford Instruments 3d models across experimental groups
    A qRT-PCR analysis IL-1β, IFN-γ, TNF-α, Aif1, CX3CR1, TREM2 relative gene expression level in the hippocampus of mouse (n = 5 mice per group, F (3, 12) = 12.51, F (3, 12) = 9.885, F (3, 12) = 22.82, F (3, 16) = 17.69, F (3, 16) = 8.891, F (3, 16) = 5.921). B Effects of NADPH treatment and LPS on oxidative stress products (SOD, GSH-PX, MDA) and CORT content in the hippocampus of mouse (n = 6 mice per group, F (3, 20) = 68.93, F (3, 20) = 50.99, F (3, 20) = 21.85, F (3, 20) = 10.52). Data are represented as means ± SEM. *P < 0.05, **P < 0.01, ***P < 0.005, ****P < 0.001 by one-way ANOVA followed by Tukey’s test. C Representative images <t>of</t> <t>microglial</t> Iba1 immunofluorescence staining and Imaris-reconstructed <t>3D</t> models across experimental groups; Scale bar = 3 μm. D Semi-automated quantification of microglial activation. Representative bar graphs of Iba1 expression and 3D morphological measurements of microglia. Each symbol represents an individual microglial cell. Data were analyzed from 5 cells per group, derived from at least 5 mice (n = 5–6 per group, intensity mean, F (3, 20) = 11.69, soma volume, F (3, 16) = 10.52, dendrite length, F (3, 19) = 20.66, No. of dendrite branch Pts, F (3, 19) = 11.57, No. of segment, F (3, 19) = 13.31, No. of dendrite terminal Pts, F (3, 19) = 15.01). E Sholl analysis of microglia. (10–20μm, *, control vs LPS+NaCl, p <0.05. 18–22μm #, LPS+NaCl vs LPS + NADPH, p <0.05). Data are represented as means ± SEM. *P < 0.05, **P < 0.01, ***P < 0.005, ****P < 0.001 by one-way ANOVA followed by Tukey’s test.
    3d Models Across Experimental Groups, supplied by Oxford Instruments, used in various techniques. Bioz Stars score: 99/100, based on 41025 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/3d models across experimental groups/product/Oxford Instruments
    Average 99 stars, based on 41025 article reviews
    3d models across experimental groups - by Bioz Stars, 2026-02
    99/100 stars

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    1) Product Images from "NADPH alleviates LPS-induced neuropathology and depression-like behaviors by suppressing microglial inflammatory response"

    Article Title: NADPH alleviates LPS-induced neuropathology and depression-like behaviors by suppressing microglial inflammatory response

    Journal: Translational Psychiatry

    doi: 10.1038/s41398-025-03761-1

    A qRT-PCR analysis IL-1β, IFN-γ, TNF-α, Aif1, CX3CR1, TREM2 relative gene expression level in the hippocampus of mouse (n = 5 mice per group, F (3, 12) = 12.51, F (3, 12) = 9.885, F (3, 12) = 22.82, F (3, 16) = 17.69, F (3, 16) = 8.891, F (3, 16) = 5.921). B Effects of NADPH treatment and LPS on oxidative stress products (SOD, GSH-PX, MDA) and CORT content in the hippocampus of mouse (n = 6 mice per group, F (3, 20) = 68.93, F (3, 20) = 50.99, F (3, 20) = 21.85, F (3, 20) = 10.52). Data are represented as means ± SEM. *P < 0.05, **P < 0.01, ***P < 0.005, ****P < 0.001 by one-way ANOVA followed by Tukey’s test. C Representative images of microglial Iba1 immunofluorescence staining and Imaris-reconstructed 3D models across experimental groups; Scale bar = 3 μm. D Semi-automated quantification of microglial activation. Representative bar graphs of Iba1 expression and 3D morphological measurements of microglia. Each symbol represents an individual microglial cell. Data were analyzed from 5 cells per group, derived from at least 5 mice (n = 5–6 per group, intensity mean, F (3, 20) = 11.69, soma volume, F (3, 16) = 10.52, dendrite length, F (3, 19) = 20.66, No. of dendrite branch Pts, F (3, 19) = 11.57, No. of segment, F (3, 19) = 13.31, No. of dendrite terminal Pts, F (3, 19) = 15.01). E Sholl analysis of microglia. (10–20μm, *, control vs LPS+NaCl, p <0.05. 18–22μm #, LPS+NaCl vs LPS + NADPH, p <0.05). Data are represented as means ± SEM. *P < 0.05, **P < 0.01, ***P < 0.005, ****P < 0.001 by one-way ANOVA followed by Tukey’s test.
    Figure Legend Snippet: A qRT-PCR analysis IL-1β, IFN-γ, TNF-α, Aif1, CX3CR1, TREM2 relative gene expression level in the hippocampus of mouse (n = 5 mice per group, F (3, 12) = 12.51, F (3, 12) = 9.885, F (3, 12) = 22.82, F (3, 16) = 17.69, F (3, 16) = 8.891, F (3, 16) = 5.921). B Effects of NADPH treatment and LPS on oxidative stress products (SOD, GSH-PX, MDA) and CORT content in the hippocampus of mouse (n = 6 mice per group, F (3, 20) = 68.93, F (3, 20) = 50.99, F (3, 20) = 21.85, F (3, 20) = 10.52). Data are represented as means ± SEM. *P < 0.05, **P < 0.01, ***P < 0.005, ****P < 0.001 by one-way ANOVA followed by Tukey’s test. C Representative images of microglial Iba1 immunofluorescence staining and Imaris-reconstructed 3D models across experimental groups; Scale bar = 3 μm. D Semi-automated quantification of microglial activation. Representative bar graphs of Iba1 expression and 3D morphological measurements of microglia. Each symbol represents an individual microglial cell. Data were analyzed from 5 cells per group, derived from at least 5 mice (n = 5–6 per group, intensity mean, F (3, 20) = 11.69, soma volume, F (3, 16) = 10.52, dendrite length, F (3, 19) = 20.66, No. of dendrite branch Pts, F (3, 19) = 11.57, No. of segment, F (3, 19) = 13.31, No. of dendrite terminal Pts, F (3, 19) = 15.01). E Sholl analysis of microglia. (10–20μm, *, control vs LPS+NaCl, p <0.05. 18–22μm #, LPS+NaCl vs LPS + NADPH, p <0.05). Data are represented as means ± SEM. *P < 0.05, **P < 0.01, ***P < 0.005, ****P < 0.001 by one-way ANOVA followed by Tukey’s test.

    Techniques Used: Quantitative RT-PCR, Gene Expression, Immunofluorescence, Staining, Activation Assay, Expressing, Derivative Assay, Control



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    3d models across experimental groups  (Oxford Instruments)
    99
    Oxford Instruments 3d models across experimental groups
    A qRT-PCR analysis IL-1β, IFN-γ, TNF-α, Aif1, CX3CR1, TREM2 relative gene expression level in the hippocampus of mouse (n = 5 mice per group, F (3, 12) = 12.51, F (3, 12) = 9.885, F (3, 12) = 22.82, F (3, 16) = 17.69, F (3, 16) = 8.891, F (3, 16) = 5.921). B Effects of NADPH treatment and LPS on oxidative stress products (SOD, GSH-PX, MDA) and CORT content in the hippocampus of mouse (n = 6 mice per group, F (3, 20) = 68.93, F (3, 20) = 50.99, F (3, 20) = 21.85, F (3, 20) = 10.52). Data are represented as means ± SEM. *P < 0.05, **P < 0.01, ***P < 0.005, ****P < 0.001 by one-way ANOVA followed by Tukey’s test. C Representative images <t>of</t> <t>microglial</t> Iba1 immunofluorescence staining and Imaris-reconstructed <t>3D</t> models across experimental groups; Scale bar = 3 μm. D Semi-automated quantification of microglial activation. Representative bar graphs of Iba1 expression and 3D morphological measurements of microglia. Each symbol represents an individual microglial cell. Data were analyzed from 5 cells per group, derived from at least 5 mice (n = 5–6 per group, intensity mean, F (3, 20) = 11.69, soma volume, F (3, 16) = 10.52, dendrite length, F (3, 19) = 20.66, No. of dendrite branch Pts, F (3, 19) = 11.57, No. of segment, F (3, 19) = 13.31, No. of dendrite terminal Pts, F (3, 19) = 15.01). E Sholl analysis of microglia. (10–20μm, *, control vs LPS+NaCl, p <0.05. 18–22μm #, LPS+NaCl vs LPS + NADPH, p <0.05). Data are represented as means ± SEM. *P < 0.05, **P < 0.01, ***P < 0.005, ****P < 0.001 by one-way ANOVA followed by Tukey’s test.
    3d Models Across Experimental Groups, supplied by Oxford Instruments, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/3d models across experimental groups/product/Oxford Instruments
    Average 99 stars, based on 1 article reviews
    3d models across experimental groups - by Bioz Stars, 2026-02
    99/100 stars
    		  Buy from Supplier

    Image Search Results


    A qRT-PCR analysis IL-1β, IFN-γ, TNF-α, Aif1, CX3CR1, TREM2 relative gene expression level in the hippocampus of mouse (n = 5 mice per group, F (3, 12) = 12.51, F (3, 12) = 9.885, F (3, 12) = 22.82, F (3, 16) = 17.69, F (3, 16) = 8.891, F (3, 16) = 5.921). B Effects of NADPH treatment and LPS on oxidative stress products (SOD, GSH-PX, MDA) and CORT content in the hippocampus of mouse (n = 6 mice per group, F (3, 20) = 68.93, F (3, 20) = 50.99, F (3, 20) = 21.85, F (3, 20) = 10.52). Data are represented as means ± SEM. *P < 0.05, **P < 0.01, ***P < 0.005, ****P < 0.001 by one-way ANOVA followed by Tukey’s test. C Representative images of microglial Iba1 immunofluorescence staining and Imaris-reconstructed 3D models across experimental groups; Scale bar = 3 μm. D Semi-automated quantification of microglial activation. Representative bar graphs of Iba1 expression and 3D morphological measurements of microglia. Each symbol represents an individual microglial cell. Data were analyzed from 5 cells per group, derived from at least 5 mice (n = 5–6 per group, intensity mean, F (3, 20) = 11.69, soma volume, F (3, 16) = 10.52, dendrite length, F (3, 19) = 20.66, No. of dendrite branch Pts, F (3, 19) = 11.57, No. of segment, F (3, 19) = 13.31, No. of dendrite terminal Pts, F (3, 19) = 15.01). E Sholl analysis of microglia. (10–20μm, *, control vs LPS+NaCl, p <0.05. 18–22μm #, LPS+NaCl vs LPS + NADPH, p <0.05). Data are represented as means ± SEM. *P < 0.05, **P < 0.01, ***P < 0.005, ****P < 0.001 by one-way ANOVA followed by Tukey’s test.

    Journal: Translational Psychiatry

    Article Title: NADPH alleviates LPS-induced neuropathology and depression-like behaviors by suppressing microglial inflammatory response

    doi: 10.1038/s41398-025-03761-1

    Figure Lengend Snippet: A qRT-PCR analysis IL-1β, IFN-γ, TNF-α, Aif1, CX3CR1, TREM2 relative gene expression level in the hippocampus of mouse (n = 5 mice per group, F (3, 12) = 12.51, F (3, 12) = 9.885, F (3, 12) = 22.82, F (3, 16) = 17.69, F (3, 16) = 8.891, F (3, 16) = 5.921). B Effects of NADPH treatment and LPS on oxidative stress products (SOD, GSH-PX, MDA) and CORT content in the hippocampus of mouse (n = 6 mice per group, F (3, 20) = 68.93, F (3, 20) = 50.99, F (3, 20) = 21.85, F (3, 20) = 10.52). Data are represented as means ± SEM. *P < 0.05, **P < 0.01, ***P < 0.005, ****P < 0.001 by one-way ANOVA followed by Tukey’s test. C Representative images of microglial Iba1 immunofluorescence staining and Imaris-reconstructed 3D models across experimental groups; Scale bar = 3 μm. D Semi-automated quantification of microglial activation. Representative bar graphs of Iba1 expression and 3D morphological measurements of microglia. Each symbol represents an individual microglial cell. Data were analyzed from 5 cells per group, derived from at least 5 mice (n = 5–6 per group, intensity mean, F (3, 20) = 11.69, soma volume, F (3, 16) = 10.52, dendrite length, F (3, 19) = 20.66, No. of dendrite branch Pts, F (3, 19) = 11.57, No. of segment, F (3, 19) = 13.31, No. of dendrite terminal Pts, F (3, 19) = 15.01). E Sholl analysis of microglia. (10–20μm, *, control vs LPS+NaCl, p <0.05. 18–22μm #, LPS+NaCl vs LPS + NADPH, p <0.05). Data are represented as means ± SEM. *P < 0.05, **P < 0.01, ***P < 0.005, ****P < 0.001 by one-way ANOVA followed by Tukey’s test.

    Article Snippet: C Representative images of microglial Iba1 immunofluorescence staining and Imaris-reconstructed 3D models across experimental groups; Scale bar = 3 μm.

    Techniques: Quantitative RT-PCR, Gene Expression, Immunofluorescence, Staining, Activation Assay, Expressing, Derivative Assay, Control